Mutations in ribosomal protein L16 and in 23S rRNA gene in Enterococcus strains for which evernimicin MICs differ
- Zarazaga, M. 1
- Tenorio, C. 1
- Del Campo, R. 1
- Ruiz-Larrea, F. 1
- Torres, C. 1
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1
Universidad de La Rioja
info
ISSN: 0066-4804
Year of publication: 2002
Volume: 46
Issue: 11
Pages: 3657-3659
Type: Article
More publications in: Antimicrobial Agents and Chemotherapy
Metrics
Cited by
JCR (Journal Impact Factor)
- Year 2002
- Journal Impact Factor: 4.215
- Journal Impact Factor without self cites: 3.333
- Article influence score: 0.0
- Best Quartile: Q1
- Area: PHARMACOLOGY & PHARMACY Quartile: Q1 Rank in area: 16/188 (Ranking edition: SCIE)
- Area: MICROBIOLOGY Quartile: Q1 Rank in area: 11/82 (Ranking edition: SCIE)
SCImago Journal Rank
- Year 2002
- SJR Journal Impact: 2.219
- Best Quartile: Q1
- Area: Infectious Diseases Quartile: Q1 Rank in area: 11/172
- Area: Pharmacology (medical) Quartile: Q1 Rank in area: 2/189
- Area: Pharmacology Quartile: Q1 Rank in area: 9/300
Abstract
Mutations in ribosomal protein L16 and in 23S rRNA were investigated in 22 Enterococcus strains of different species and for which the MICs of evernimicin differ (MICs, 0.023 to 16 μg/ml). Amino acid changes (Arg56His, Ile52Thr, or Arg51His) in protein L16 were found in seven strains, and a nucleotide G2535A mutation in 23S rRNA was found in 1 strain among 13 for which the MICs are ≥1 μg/ml.