Ethyl (3s,4aR,6S,8aR)-6-(4-ethoxycar-bonylimidazol-1-ylmethyl) decahydroiso-quinoline-3-carboxylic ester: A prodrug of a GluR5 kainate receptor antagonist active in two animal models of acute migraine

  1. Filla, S.A.
  2. Winter, M.A.
  3. Johnson, K.W.
  4. Bleakman, D.
  5. Bell, M.G.
  6. Bleisch, T.J.
  7. Castaño, A.M.
  8. Clemens-Smith, A.
  9. Del Prado, M.
  10. Dieckman, D.K.
  11. Dominguez, E.
  12. Escribano, A.
  13. Ho, K.H.
  14. Hudziak, K.J.
  15. Katofiasc, M.A.
  16. Martinez-Perez, J.A.
  17. Mateo, A.
  18. Mathes, B.M.
  19. Mattiuz, E.L.
  20. Ogden, A.M.L.
  21. Phebus, L.A.
  22. Stack, D.R.
  23. Stratford, R.E.
  24. Ornstein, P.L.
Revue:
Journal of Medicinal Chemistry

ISSN: 0022-2623

Année de publication: 2002

Volumen: 45

Número: 20

Pages: 4383-4386

Type: Article

DOI: 10.1021/JM025548Q GOOGLE SCHOLAR