Risk of bias in dentistry-related randomized controlled trials in spanish language journals

  1. Conchita Martin 1
  2. Isabel Delgado 1
  3. Rosa Rojo 2
  4. Rafael Souper 3
  5. Carola Veliz 3
  6. Josefina Salazar 4
  7. Marlene Diaz 5
  8. Javier Cuellar 6
  9. Matías Dallaserra 3
  10. Xavier Bofill 4
  11. Josefina Bendersky 3
  12. Sebastian Zapata 3
  13. Julio Villanueva 3
  1. 1 Universidad Complutense de Madrid

    Universidad Complutense de Madrid

    Madrid, España

    ROR 02p0gd045

  2. 2 Universidad Rey Juan Carlos

    Universidad Rey Juan Carlos

    Madrid, España

    ROR https://ror.org/01v5cv687

  3. 3 Universidad de Chile

    Universidad de Chile

    Santiago de Chile, Chile

    ROR https://ror.org/047gc3g35

  4. 4 Hospital San Borja Arriarán

    Hospital San Borja Arriarán

    Santiago de Chile, Chile

    ROR https://ror.org/04qdwp261

  5. 5 Sant Pau Biomedical Research Institute (IIB Sant Pau) and CIBER Epidemiología y Salud Pública (CIBERESP)
  6. 6 Univiersity of Chile
International journal of interdisciplinary dentistry

ISSN: 2452-5588 2452-5596

Year of publication: 2023

Volume: 16

Issue: 2

Pages: 137-141

Type: Article

DOI: 10.4067/S2452-55882023000200137 DIALNET GOOGLE SCHOLAR lock_openOpen access editor

More publications in: International journal of interdisciplinary dentistry


ABSTRACT: Objectives: To assess the risk of bias (RoB) of randomized controlled trials (RCTs) published in dental journals in the Spanish language. Methods: A systematic retrospective survey was conducted of all RCTs published from 1980 to 2019 in dentistry Spanish and Latin American journals. We extracted data and performed RoB assessments using the Cochrane Risk of Bias tool. Results: 292 RCTs published in 51 journals were included. The best-rated domains were incomplete outcome data, selective reporting, and other biases. The domains assessed with higher proportions of an unclear or high risk of bias were sequence generation, allocation concealment, and blinding of outcome assessment. There is a low proportion of RCTs published in Spanish language journals. However, the number has been increasing over the years, and the low risk of bias assessment rates across domains show an increasing trend. Conclusions: A low percentage of Spanish-language dental journals issue RCTs. Our assessment of these RCTs’ RoB suggests higher difficulties in the design and conduction phase than in the posterior reporting stage.

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