Publicacions en col·laboració amb investigadors/es de Centro Nacional de Microbiología (28)

2012

  1. Intersectin 1 enhances Cbl ubiquitylation of epidermal growth factor receptor through regulation of sprouty2-Cbl interaction

    Molecular and Cellular Biology, Vol. 32, Núm. 4, pp. 817-825

2011

  1. Sprouty2 and spred1-2 proteins inhibit the activation of the ERK pathway elicited by cyclopentenone prostanoids

    PLoS ONE, Vol. 6, Núm. 2

  2. The C-terminus of H-ras as a target for the covalent binding of reactive compounds modulating Ras-dependent pathways

    PLoS ONE, Vol. 6, Núm. 1

2010

  1. SPROUTY-2 and E-cadherin regulate reciprocally and dictate colon cancer cell tumourigenicity

    Oncogene, Vol. 29, Núm. 34, pp. 4800-4813

2009

  1. Cell density-dependent inhibition of epidermal growth factor receptor signaling by p38α mitogen-activated protein kinase via sprouty2 downregulation

    Molecular and Cellular Biology, Vol. 29, Núm. 12, pp. 3332-3343

  2. SJ23B, a jatrophane diterpene activates classical PKCs and displays strong activity against HIV in vitro

    Biochemical Pharmacology, Vol. 77, Núm. 6, pp. 965-978

2008

  1. E1a gene expression blocks the ERK1/2 signaling pathway by promoting nuclear localization and MKP up-regulation: Implication in v-H-Ras-induced senescence

    Journal of Biological Chemistry, Vol. 283, Núm. 19, pp. 13450-13458

  2. Endothelial nitric oxide synthase regulates N-Ras activation on the Golgi complex of antigen-stimulated T cells

    Proceedings of the National Academy of Sciences of the United States of America, Vol. 105, Núm. 30, pp. 10507-10512

  3. Nuclear exclusion of forkhead box O and Elk1 and activation of nuclear factor-κB are required for C2C12-RasV12C40 myoblast differentiation

    Endocrinology, Vol. 149, Núm. 2, pp. 793-801

  4. Plitidepsin has a dual effect inhibiting cell cycle and inducing apoptosis via Rac1/c-Jun NH2-terminal kinase activation in human melanoma cells

    Journal of Pharmacology and Experimental Therapeutics, Vol. 324, Núm. 3, pp. 1093-1101

2007

  1. Modification and activation of Ras proteins by electrophilic prostanoids with different structure are site-selective

    Biochemistry, Vol. 46, Núm. 22, pp. 6607-6616

  2. Sprouty2 binds Grb2 at two different proline-rich regions, and the mechanism of ERK inhibition is independent of this interaction

    Cellular Signalling, Vol. 19, Núm. 11, pp. 2277-2285

2006

  1. Aplidin® induces JNK-dependent apoptosis in human breast cancer cells via alteration of glutathione homeostasis, Rac1 GTPase activation, and MKP-1 phosphatase downregulation

    Cell Death and Differentiation, Vol. 13, Núm. 11, pp. 1968-1981

  2. Grb2 is a negative modulator of the intrinsic Ras-GEF activity of hSos1

    Molecular Biology of the Cell, Vol. 17, Núm. 8, pp. 3591-3597

  3. Plitidepsin cellular binding and Rac1/JNK pathway activation depend on membrane cholesterol content

    Molecular Pharmacology, Vol. 70, Núm. 5, pp. 1654-1663

  4. Potentiation of tumor formation by topical administration of 15-deoxy-Δ12,14-prostaglandin J2 in a model of skin carcinogenesis

    Carcinogenesis, Vol. 27, Núm. 2, pp. 328-336

  5. The histone acetyltransferases CBP/p300 are degraded in NIH 3T3 cells by activation of Ras signalling pathway

    Biochemical Journal, Vol. 398, Núm. 2, pp. 215-224

2005

  1. Full activation of PKB/Akt in response to insulin or ionizing radiation is mediated through ATM

    Journal of Biological Chemistry, Vol. 280, Núm. 6, pp. 4029-4036

  2. Immortalized mouse mammary fibroblasts lacking dioxin receptor have impaired tumorigenicity in a subcutaneous mouse xenograft model

    Journal of Biological Chemistry, Vol. 280, Núm. 31, pp. 28731-28741

  3. PKB/Akt media la radio sensibilidad asociada a ataxia telangiectasia

    Oncologia, Vol. 28, Núm. 7, pp. 29-37