GluK1 antagonists from 6-(carboxy)phenyl decahydroisoquinoline derivatives. SAR and evaluation of a prodrug strategy for oral efficacy in pain models

  1. Martinez-Perez, J.A.
  2. Iyengar, S.
  3. Shannon, H.E.
  4. Bleakman, D.
  5. Alt, A.
  6. Arnold, B.M.
  7. Bell, M.G.
  8. Bleisch, T.J.
  9. Castaño, A.M.
  10. Del Prado, M.
  11. Dominguez, E.
  12. Escribano, A.M.
  13. Filla, S.A.
  14. Ho, K.H.
  15. Hudziak, K.J.
  16. Jones, C.K.
  17. Mateo, A.
  18. Mathes, B.M.
  19. Mattiuz, E.L.
  20. Ogden, A.M.L.
  21. Simmons, R.M.A.
  22. Stack, D.R.
  23. Stratford, R.E.
  24. Winter, M.A.
  25. Wu, Z.
  26. Ornstein, P.L.
  27. Show all authors +
Journal:
Bioorganic and Medicinal Chemistry Letters

ISSN: 0960-894X 1464-3405

Year of publication: 2013

Volume: 23

Issue: 23

Pages: 6459-6462

Type: Article

DOI: 10.1016/J.BMCL.2013.09.046 GOOGLE SCHOLAR